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Journal: Biophysical Journal
Article Title: The Elementary Mass Action Rate Constants of P-gp Transport for a Confluent Monolayer of MDCKII-hMDR1 Cells
doi: 10.1529/biophysj.104.045633
Figure Lengend Snippet: Coefficients of variation between the data, CV, and the 729 Run I fits to the 90 μM amprenavir data are plotted in a rank order, from best, CV ∼ 0.03, to worst, where CV > 0.4. Fits with a CV < 0.05 are visually very good. The rank-ordered first 609 fits essentially give the same curve, but from a wide range of parameters. Subsequent rank-ordered fits tracked increasingly worse fits, because MATLAB fminssearch was stuck in a local minimum. Fits to the right of the cut were discarded.
Article Snippet: 10 , computes the CV between the data and the simulation, and then the
Techniques: